Term Information

Accession
GO:0061157
Name
mRNA destabilization
Ontology
biological_process
Synonyms
None
Alternate IDs
None
Definition
Any process that decreases the stability of an mRNA molecule, making it more vulnerable to degradative processes. Messenger RNA is the intermediate molecule between DNA and protein. It includes UTR and coding sequences. It does not contain introns. Source: GOC:dph, GOC:jh
Comment
None
History
See term history for GO:0061157 at QuickGO
Subset
None
Feedback
Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

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Parents of mRNA destabilization (GO:0061157)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
mRNA destabilization [is_a relation] is_a  regulation of mRNA stability (GO:0043488)
mRNA destabilization [is_a relation] is_a  RNA destabilization (GO:0050779)
mRNA destabilization [is_a relation] is_a  negative regulation of translation (GO:0017148)
mRNA destabilization [is_a relation] is_a  positive regulation of mRNA catabolic process (GO:0061014)
Children of mRNA destabilization (GO:0061157)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
global gene silencing by mRNA cleavage (GO:0098795) [BFO:0000051 relation] BFO:0000051  mRNA destabilization
3'-UTR-mediated mRNA destabilization (GO:0061158) [is_a relation] is_a  mRNA destabilization
siRNA-mediated gene silencing by mRNA destabilization (GO:0090625) [is_a relation] is_a  mRNA destabilization
polyadenylation-dependent mRNA catabolic process (GO:0071047) [is_a relation] is_a  mRNA destabilization
polyuridylation-dependent mRNA catabolic process (GO:1990074) [is_a relation] is_a  mRNA destabilization
nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (GO:0000288) [is_a relation] is_a  mRNA destabilization
piRNA-mediated gene silencing by mRNA destabilization (GO:0140991) [is_a relation] is_a  mRNA destabilization
miRNA-mediated gene silencing by mRNA destabilization (GO:0035279) [is_a relation] is_a  mRNA destabilization
None.