Term Information

Accession
GO:0000288
Name
nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
Ontology
biological_process
Synonyms
deadenylation-dependent mRNA decay, mRNA breakdown, deadenylation-dependent decay, mRNA catabolic process, deadenylation-dependent, mRNA catabolic process, deadenylylation-dependent, mRNA catabolism, deadenylation-dependent, mRNA catabolism, deadenylylation-dependent, mRNA degradation, deadenylation-dependent decay, nuclear mRNA catabolic process, deadenylation-dependent decay
Alternate IDs
None
Definition
A major pathway of degradation of nuclear-transcribed mRNAs that proceeds through a series of ordered steps that includes poly(A) tail shortening and that can regulate mRNA stability. Source: GOC:krc, GOC:jp
Comment
None
History
See term history for GO:0000288 at QuickGO
Subset
None
Feedback
Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

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Parents of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (GO:0000288)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [is_a relation] is_a  mRNA destabilization (GO:0061157)
nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [is_a relation] is_a  nuclear-transcribed mRNA catabolic process (GO:0000956)
Children of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (GO:0000288)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
nuclear-transcribed mRNA poly(A) tail shortening (GO:0000289) [BFO:0000050 relation] BFO:0000050  nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
deadenylation-dependent decapping of nuclear-transcribed mRNA (GO:0000290) [BFO:0000050 relation] BFO:0000050  nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (GO:1900152) [RO:0002212 relation] RO:0002212  nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (GO:1900153) [RO:0002213 relation] RO:0002213  nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (GO:1900151) [RO:0002211 relation] RO:0002211  nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
exonucleolytic catabolism of deadenylated mRNA (GO:0043928) [BFO:0000050 relation] BFO:0000050  nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
None.