Term Information

Accession
GO:0031047
Name
regulatory ncRNA-mediated gene silencing
Ontology
biological_process
Synonyms
RNA-dependent gene silencing, RNA-mediated gene silencing, gene silencing by RNA
Alternate IDs
None
Definition
A process in which an regulatory non-coding RNA molecule reduces expression of target genes. This can occur pre-transcriptionally by assembly of heterochromatin and prevention of transcription or co- or post-transcriptionally by targeting RNAs for degradation or by interfering with splicing or translation. This process starts once the inhibitory RNA molecule has been transcribed, and includes processing of the RNA such as cleavage, modifications, transport from the nucleus to the cytoplasm, loading onto the RISC complex, and the effect on transcription or translation. Source: PMID:15020054
Comment
None
History
See term history for GO:0031047 at QuickGO
Subset
goslim_drosophila
goslim_generic
Feedback
Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

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Parents of regulatory ncRNA-mediated gene silencing (GO:0031047)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
regulatory ncRNA-mediated gene silencing [is_a relation] is_a  negative regulation of gene expression (GO:0010629)
Children of regulatory ncRNA-mediated gene silencing (GO:0031047)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
negative regulation of gene silencing by regulatory ncRNA (GO:0060967) [RO:0002212 relation] RO:0002212  regulatory ncRNA-mediated gene silencing
co-transcriptional gene silencing by RNA interference machinery (GO:0033562) [is_a relation] is_a  regulatory ncRNA-mediated gene silencing
regulatory ncRNA-mediated heterochromatin formation (GO:0031048) [is_a relation] is_a  regulatory ncRNA-mediated gene silencing
regulatory ncRNA-mediated post-transcriptional gene silencing (GO:0035194) [is_a relation] is_a  regulatory ncRNA-mediated gene silencing
regulatory ncRNA processing (GO:0070918) [BFO:0000050 relation] BFO:0000050  regulatory ncRNA-mediated gene silencing
RISC complex assembly (GO:0070922) [BFO:0000050 relation] BFO:0000050  regulatory ncRNA-mediated gene silencing
target-directed miRNA degradation (GO:0140958) [is_a relation] is_a  regulatory ncRNA-mediated gene silencing
regulation of gene silencing by regulatory ncRNA (GO:0060966) [RO:0002211 relation] RO:0002211  regulatory ncRNA-mediated gene silencing
None.