Term Information

Accession
GO:0140958
Name
target-directed miRNA degradation
Ontology
biological_process
Synonyms
TDMD, target-directed microRNA degradation
Alternate IDs
None
Definition
The process in which a miRNA is targeted for degradation by a non-coding RNA or mRNA. The binding of an RNA to a target miRNA within a RISC complex results in either ubiquitin-mediated degradation of AGO protein or the displacement of the 3' end of the miRNA, exposing it to nucleases. Source: PMID:33184237, PMID:36150386
Comment
None
History
See term history for GO:0140958 at QuickGO
Subset
None
Feedback
Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

Filter results

Loading...
pending...
Parents of target-directed miRNA degradation (GO:0140958)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
target-directed miRNA degradation [is_a relation] is_a  regulatory ncRNA-mediated gene silencing (GO:0031047)
target-directed miRNA degradation [is_a relation] is_a  miRNA catabolic process (GO:0010587)
target-directed miRNA degradation [is_a relation] is_a  post-transcriptional gene silencing (GO:0016441)

This term has no children.

None.