Term Information

Accession
GO:0140958
Name
target-directed miRNA degradation
Ontology
biological_process
Synonyms
TDMD, target-directed microRNA degradation
Alternate IDs
None
Definition
The process in which a miRNA is targeted for degradation by a non-coding RNA or mRNA. The binding of an RNA to a target miRNA within a RISC complex results in either ubiquitin-mediated degradation of AGO protein or the displacement of the 3' end of the miRNA, exposing it to nucleases. Source: PMID:33184237, PMID:36150386
Comment
None
History
See term history for GO:0140958 at QuickGO
Subset
None
Feedback
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Parents of target-directed miRNA degradation (GO:0140958)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
target-directed miRNA degradation [is_a relation] is_a  miRNA catabolic process (GO:0010587)
target-directed miRNA degradation [is_a relation] is_a  regulatory ncRNA-mediated gene silencing (GO:0031047)
target-directed miRNA degradation [is_a relation] is_a  post-transcriptional gene silencing (GO:0016441)

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None.