RISC assembly, gene silencing by RNA, small RNA loading onto RISC, small RNA loading onto RISC, miRNA loading onto RISC, siRNA loading onto RISC involved in RNA interference, siRNA loading onto RISC involved in gene silencing by small RNA, miRISC assembly
Alternate IDs
GO:0035280, GO:0070923, GO:0035087
Definition
The process in which a single-stranded small RNA is incorporated within the RNA-initiated silencing complex (RISC). The assembly includes the maturation of the small RNA, the stabilization of the complex by accessory proteins of the RISC complex, duplex separation and the release of the second strand, forming a base-pairing completent complex that mediates gene silencing by small RNA.
Source:PMID:27184117,
PMID:14512631,
PMID:14744438,
PMID:22233755,
PMID:19239886