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kidney cortex tubule cell dedifferentiation

Term Information

Accession
GO:0160029
Name
kidney cortex tubule cell dedifferentiation
Ontology
biological_process
Synonyms
None
Alternate IDs
None
Definition
The process in which a kidney cortex tubule cell (specialized epithelial cell of the kidney) loses the structural or functional features that characterize it in the mature organism, or some other relatively stable phase of the organism's life history. Under certain conditions, these cells can revert back to the features of the stem cells that were their ancestors. Source: PMID:31847447, PMID:18987110
Comment
Following injury, renal cortex tubular epithelial cell appears to be undergoing epithelial-mesenchymal transition, detected by overexpression of vimentin.
History
See term history for GO:0160029 at QuickGO
Subset
None
Feedback
Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

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Parents of kidney cortex tubule cell dedifferentiation (GO:0160029)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
kidney cortex tubule cell dedifferentiation [is_a relation] is_a  cell dedifferentiation (GO:0043697)

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None.