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cell dedifferentiation

Term Information

Accession
GO:0043697
Name
cell dedifferentiation
Ontology
biological_process
Synonyms
None
Alternate IDs
None
Definition
The process in which a specialized cell loses the structural or functional features that characterize it in the mature organism, or some other relatively stable phase of the organism's life history. Under certain conditions, these cells can revert back to the features of the stem cells that were their ancestors. Source: GOC:dph, GOC:pg
Comment
Note that this term should be used to annotate gene products involved in dedifferentiation that occurs as part of a normal process, such as regeneration. It should not be used for dedifferentiation that occurs in an abnormal or disease state such as cancer.
History
See term history for GO:0043697 at QuickGO
Subset
None
Feedback
Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

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Parents of cell dedifferentiation (GO:0043697)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
cell dedifferentiation [is_a relation] is_a  dedifferentiation (GO:0043696)
cell dedifferentiation [is_a relation] is_a  cellular developmental process (GO:0048869)
Children of cell dedifferentiation (GO:0043697)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
hepatocyte dedifferentiation (GO:1990828) [is_a relation] is_a  cell dedifferentiation
cell dedifferentiation involved in phenotypic switching (GO:0090678) [is_a relation] is_a  cell dedifferentiation
kidney cortex tubule cell dedifferentiation (GO:0160029) [is_a relation] is_a  cell dedifferentiation
None.