Term Information

Accession
GO:0140896
Name
cGAS/STING signaling pathway
Ontology
biological_process
Synonyms
None
Alternate IDs
None
Definition
The series of molecular signals initiated by the binding of a double-stranded DNA or RNA from another organism to cytosolic cyclic GMP-AMP (cGAMP) synthase (cGAS) that activates innate immune responses through production of the second messenger cGAMP, which activates the adaptor STING. Source: PMID:34261128, PMID:34261127, PMID:27648547
Comment
None
History
See term history for GO:0140896 at QuickGO
Subset
None
Feedback
Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

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Parents of cGAS/STING signaling pathway (GO:0140896)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
cGAS/STING signaling pathway [is_a relation] is_a  cytosolic pattern recognition receptor signaling pathway (GO:0002753)
Children of cGAS/STING signaling pathway (GO:0140896)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
negative regulation of cGAS/STING signaling pathway (GO:0160049) [RO:0002212 relation] RO:0002212  cGAS/STING signaling pathway
None.