Term Information

Accession
GO:0101019
Name
nucleolar exosome (RNase complex)
Ontology
cellular_component
Synonyms
None
Alternate IDs
None
Definition
A ribonuclease complex that has 3-prime to 5-prime distributive hydrolytic exoribonuclease activity and in some taxa (e.g. yeast) endoribonuclease activity, producing 5-prime-phosphomonoesters. Participates in a multitude of cellular RNA processing and degradation events preventing nuclear export and/or translation of aberrant RNAs. Restricted to processing linear and circular single-stranded RNAs (ssRNA) only. RNAs with complex secondary structures may have to be unwound or pre-processed by co-factors prior to entering the complex, esp if the 3-prime end is structured. Source: PMID:26726035, PMID:17174896, PMID:20531386
Comment
None
History
See term history for GO:0101019 at QuickGO
Subset
None
Feedback
Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

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Parents of nucleolar exosome (RNase complex) (GO:0101019)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
nucleolar exosome (RNase complex) [BFO:0000050 relation] BFO:0000050  nucleolus (GO:0005730)
nucleolar exosome (RNase complex) [is_a relation] is_a  nuclear exosome (RNase complex) (GO:0000176)

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None.