Term Information

Accession
GO:0005730
Name
nucleolus
Ontology
cellular_component
Synonyms
None
Alternate IDs
None
Definition
A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome. Source: ISBN:0198506732
Comment
None
History
See term history for GO:0005730 at QuickGO
Subset
goslim_chembl
goslim_drosophila
goslim_generic
goslim_plant
goslim_yeast
goslim_candida
goslim_pir
Feedback
Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

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Parents of nucleolus (GO:0005730)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
nucleolus [BFO:0000050 relation] BFO:0000050  nuclear lumen (GO:0031981)
nucleolus [is_a relation] is_a  intracellular non-membrane-bounded organelle (GO:0043232)
Children of nucleolus (GO:0005730)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
PeBoW complex (GO:0070545) [BFO:0000050 relation] BFO:0000050  nucleolus
nucleolar exosome (RNase complex) (GO:0101019) [BFO:0000050 relation] BFO:0000050  nucleolus
box H/ACA snoRNP complex (GO:0031429) [BFO:0000050 relation] BFO:0000050  nucleolus
granular component (GO:0001652) [BFO:0000050 relation] BFO:0000050  nucleolus
t-UTP complex (GO:0034455) [BFO:0000050 relation] BFO:0000050  nucleolus
fibrillar center (GO:0001650) [BFO:0000050 relation] BFO:0000050  nucleolus
nucleolar chromatin (GO:0030874) [BFO:0000050 relation] BFO:0000050  nucleolus
Mpp10 complex (GO:0034457) [BFO:0000050 relation] BFO:0000050  nucleolus
Pwp2p-containing subcomplex of 90S preribosome (GO:0034388) [BFO:0000050 relation] BFO:0000050  nucleolus
RNA polymerase I complex (GO:0005736) [BFO:0000050 relation] BFO:0000050  nucleolus
nucleolar ribonuclease P complex (GO:0005655) [BFO:0000050 relation] BFO:0000050  nucleolus
nucleolar preribosome (GO:0030685) [BFO:0000050 relation] BFO:0000050  nucleolus
UTP-C complex (GO:0034456) [BFO:0000050 relation] BFO:0000050  nucleolus
B-WICH complex (GO:0110016) [BFO:0000050 relation] BFO:0000050  nucleolus
RENT complex (GO:0030869) [BFO:0000050 relation] BFO:0000050  nucleolus
RNA polymerase I transcription regulator complex (GO:0000120) [BFO:0000050 relation] BFO:0000050  nucleolus
eNoSc complex (GO:0061773) [BFO:0000050 relation] BFO:0000050  nucleolus
dense fibrillar component (GO:0001651) [BFO:0000050 relation] BFO:0000050  nucleolus
NIF_Subcellular
sao1820400233
Wikipedia
Nucleolus