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execution phase of apoptosis

Term Information

Accession
GO:0097194
Name
execution phase of apoptosis
Ontology
biological_process
Synonyms
execution phase of apoptotic process, apoptosis
Alternate IDs
None
Definition
A stage of the apoptotic process that starts with the controlled breakdown of the cell through the action of effector caspases or other effector molecules (e.g. cathepsins, calpains etc.). Key steps of the execution phase are rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died. Source: PMID:21760595, GOC:mtg_apoptosis
Comment
None
History
See term history for GO:0097194 at QuickGO
Subset
None
Feedback
Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

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Parents of execution phase of apoptosis (GO:0097194)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
execution phase of apoptosis [BFO:0000050 relation] BFO:0000050  apoptotic process (GO:0006915)
execution phase of apoptosis [is_a relation] is_a  cellular process (GO:0009987)
execution phase of apoptosis [BFO:0000051 relation] BFO:0000051  bleb assembly (GO:0032060)
Children of execution phase of apoptosis (GO:0097194)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
regulation of execution phase of apoptosis (GO:1900117) [RO:0002211 relation] RO:0002211  execution phase of apoptosis
positive regulation of execution phase of apoptosis (GO:1900119) [RO:0002213 relation] RO:0002213  execution phase of apoptosis
phosphatidylserine exposure on apoptotic cell surface (GO:0070782) [BFO:0000050 relation] BFO:0000050  execution phase of apoptosis
negative regulation of execution phase of apoptosis (GO:1900118) [RO:0002212 relation] RO:0002212  execution phase of apoptosis
cysteine-type endopeptidase activity involved in execution phase of apoptosis (GO:0097200) [BFO:0000050 relation] BFO:0000050  execution phase of apoptosis
cellular component disassembly involved in execution phase of apoptosis (GO:0006921) [BFO:0000050 relation] BFO:0000050  execution phase of apoptosis
None.