Term Information

Accession
GO:0071751
Name
secretory IgA immunoglobulin complex
Ontology
cellular_component
Synonyms
sIgA antibody, secretory IgA antibody, sIgA1 antibody
Alternate IDs
None
Definition
A polymeric IgA immunoglobulin complex that is complexed with one chain of secretory component (SC). Polymeric IgA is present in mucosal areas, having been transported via a transcytosis mechanism in mucosal epithelial cells relying on the polymeric Ig receptor, a portion of which then remains bound to the polymeric IgA as secretory component. Source: ISBN:0781765196, PMID:16362985, GOC:add
Comment
Note that an IgA immunoglobulin complex has the function of antigen binding if a suitable antigen is available. In human only the IgA1 isotype in the polymeric form is capable of becoming secretory IgA.
History
See term history for GO:0071751 at QuickGO
Subset
None
Feedback
Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

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Parents of secretory IgA immunoglobulin complex (GO:0071751)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
secretory IgA immunoglobulin complex [is_a relation] is_a  polymeric IgA immunoglobulin complex (GO:0071749)
Children of secretory IgA immunoglobulin complex (GO:0071751)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
secretory dimeric IgA immunoglobulin complex (GO:0071752) [is_a relation] is_a  secretory IgA immunoglobulin complex
None.