Planteome: Term Details for "dimeric IgA immunoglobulin complex" (GO:0071750)

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Term Information

Accession: GO:0071750
Name: dimeric IgA immunoglobulin complex
Ontology: cellular_component
Synonyms: dimeric IgA antibody, dimeric IgA1 antibody
Alternate IDs: None
Definition: A protein complex composed of two monomeric IgA immunoglobulin complexes linked through both direct disulfide bonds and through a disulfide binded monomer of J chain acting as a bridge. Each IgA monomer consists of two identical immunoglobulin heavy chains of an IgA isotype and two identical immunoglobulin light chains, held together by disulfide bonds. Dimeric IgA is sometimes complexed additionally with secretory component, and present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph. Source: ISBN:0781765196, PMID:16362985, GOC:add
Comment: Note that an IgA immunoglobulin complex has the function of antigen binding if a suitable antigen is available. Dimeric IgA is by far the most common form of polymeric IgA. In human only the IgA1 isotype is capable of a dimeric form.
History: See term history for GO:0071750 at QuickGO
Subset: None
Related: Link to all annotated objects annotated to dimeric IgA immunoglobulin complex.; Link to all direct and indirect annotations to dimeric IgA immunoglobulin complex.; Link to all direct and indirect annotations download (limited to first 10,000) for dimeric IgA immunoglobulin complex.
Feedback: Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.