Term Information

Accession
GO:0070479
Name
nuclear-transcribed mRNA catabolic process, 5'-3' exonucleolytic nonsense-mediated decay
Ontology
biological_process
Synonyms
5'-3' NMD, 5'-3' nonsense-mediated decay, 5'-3' nonsense-mediated mRNA decay, nuclear-transcribed mRNA breakdown, 5'-3' exonucleolytic nonsense-mediated decay, nuclear-transcribed mRNA catabolism, 5'-3' exonucleolytic nonsense-mediated decay, nuclear-transcribed mRNA degradation, 5'-3' exonucleolytic nonsense-mediated decay
Alternate IDs
None
Definition
The chemical reactions and pathways resulting in the breakdown of the nuclear-transcribed mRNA transcript body of an mRNA in which an amino-acid codon has changed to a nonsense codon; occurs when the 5' end is not protected by a 5'-cap; degradation proceeds in the 5' to 3' direction. Source: PMID:18554525
Comment
None
History
See term history for GO:0070479 at QuickGO
Subset
None
Feedback
Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

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Parents of nuclear-transcribed mRNA catabolic process, 5'-3' exonucleolytic nonsense-mediated decay (GO:0070479)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
nuclear-transcribed mRNA catabolic process, 5'-3' exonucleolytic nonsense-mediated decay [is_a relation] is_a  nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)
nuclear-transcribed mRNA catabolic process, 5'-3' exonucleolytic nonsense-mediated decay [is_a relation] is_a  exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-independent decay (GO:0070480)
nuclear-transcribed mRNA catabolic process, 5'-3' exonucleolytic nonsense-mediated decay [is_a relation] is_a  nuclear-transcribed mRNA catabolic process, exonucleolytic, 5'-3' (GO:0034428)

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