Term Information

Accession
GO:0061779
Name
Tapasin-ERp57 complex
Ontology
cellular_component
Synonyms
None
Alternate IDs
None
Definition
Subunit of the MHC class I peptide loading complex (GO:0042824) (=PLC) involved in the assembly of the heavy-chain-beta2-microglobulin dimers of the MHC class I molecules that fold with eight to ten residue peptides in the endoplasmic reticulum. Required for the inhibition of the reduction of the disulfide bonds of the heavy chains and the assembly and stabilization of the PLC, suggesting it may play a structural rather than a catalytic role. Source: GOC:dph, PMID:17603487, Intact:EBI-9013963, Intact:EBI-11896237, GOC:bhm
Comment
None
History
See term history for GO:0061779 at QuickGO
Subset
None
Feedback
Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

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Parents of Tapasin-ERp57 complex (GO:0061779)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
Tapasin-ERp57 complex [is_a relation] is_a  endoplasmic reticulum protein-containing complex (GO:0140534)
Tapasin-ERp57 complex [BFO:0000050 relation] BFO:0000050  MHC class I peptide loading complex (GO:0042824)
Tapasin-ERp57 complex [is_a relation] is_a  membrane protein complex (GO:0098796)

This term has no children.

None.