Planteome: Term Details for "MHC class I peptide loading complex" (GO:0042824)

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Term Information

Accession: GO:0042824
Name: MHC class I peptide loading complex
Ontology: cellular_component
Synonyms: peptide-loading complex, PLC
Alternate IDs: None
Definition: A large, multisubunit complex which consists of the MHC class I-beta 2 microglobulin dimer, the transporter associated with antigen presentation (TAP), tapasin (an MHC-encoded membrane protein), the chaperone calreticulin and the thiol oxidoreductase ERp57. Functions in the assembly of peptides with newly synthesized MHC class I molecules. Source: GOC:jl, PMID:10631934
Comment: Note that although this complex is located in the endoplasmic reticulum, there is some evidence that it may also be found in the Golgi.
History: See term history for GO:0042824 at QuickGO
Subset: goslim_pir
Related: Link to all annotated objects annotated to MHC class I peptide loading complex.; Link to all direct and indirect annotations to MHC class I peptide loading complex.; Link to all direct and indirect annotations download (limited to first 10,000) for MHC class I peptide loading complex.
Feedback: Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

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GO:0110165 cellular anatomical entity
GO:0005622 intracellular anatomical structure
GO:0043226 organelle
GO:0005575 cellular_component
GO:0043229 intracellular organelle
GO:0043227 membrane-bounded organelle
GO:0005737 cytoplasm
GO:0012505 endomembrane system
GO:0005783 endoplasmic reticulum
GO:0043231 intracellular membrane-bounded organelle
GO:0016020 membrane
GO:0031984 organelle subcompartment
GO:0098827 endoplasmic reticulum subcompartment
GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network
GO:0031090 organelle membrane
GO:0032991 protein-containing complex
GO:0005789 endoplasmic reticulum membrane
GO:0140534 endoplasmic reticulum protein-containing complex
GO:0098796 membrane protein complex
GO:0042824 MHC class I peptide loading complex
GO:0042825 TAP complex
GO:0061779 Tapasin-ERp57 complex

Parents of MHC class I peptide loading complex (GO:0042824)

subject	relation	object
MHC class I peptide loading complex	is_a	endoplasmic reticulum protein-containing complex (GO:0140534)
MHC class I peptide loading complex	is_a	membrane protein complex (GO:0098796)
MHC class I peptide loading complex	BFO:0000050	endoplasmic reticulum membrane (GO:0005789)

Children of MHC class I peptide loading complex (GO:0042824)

subject	relation	object
TAP complex (GO:0042825)	BFO:0000050	MHC class I peptide loading complex
Tapasin-ERp57 complex (GO:0061779)	BFO:0000050	MHC class I peptide loading complex

MHC class I peptide loading complex

Term Information

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Parents of MHC class I peptide loading complex (GO:0042824)

Children of MHC class I peptide loading complex (GO:0042824)

None.