Term Information

Accession
GO:0044823
Name
retroviral integrase activity
Ontology
molecular_function
Synonyms
None
Alternate IDs
None
Definition
Catalysis of the covalent insertion of double-stranded retroviral DNA into host DNA. Proceeds by an endonucleolytic cleavage at each 3'-OH extremity of the viral genome, named 3'-processing, followed by a strand transfer reaction leading to the insertion of the processed viral DNA into the target DNA by a trans-esterification mechanism. Source: PMID:19091057
Comment
None
History
See term history for GO:0044823 at QuickGO
Subset
None
Feedback
Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

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Parents of retroviral integrase activity (GO:0044823)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
retroviral integrase activity [is_a relation] is_a  integrase activity (GO:0008907)
retroviral integrase activity [BFO:0000050 relation] BFO:0000050  viral genome integration into host DNA (GO:0044826)
Children of retroviral integrase activity (GO:0044823)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
retroviral 3' processing activity (GO:0044824) [BFO:0000050 relation] BFO:0000050  retroviral integrase activity
None.