Term Information

Accession
GO:0043224
Name
nuclear SCF ubiquitin ligase complex
Ontology
cellular_component
Synonyms
nuclear SCF complex, nuclear Skp1/Cul1/F-box protein complex, nuclear cullin complex
Alternate IDs
None
Definition
A ubiquitin ligase complex, located in the nucleus, in which a cullin from the Cul1 subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by a Skp1 adaptor and an F-box protein. SCF complexes are involved in targeting proteins for degradation by the proteasome. The best characterized complexes are those from yeast and mammals (with core subunits named Cdc53/Cul1, Rbx1/Hrt1/Roc1). Source: PMID:15688063, PMID:15571813
Comment
None
History
See term history for GO:0043224 at QuickGO
Subset
None
Feedback
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Parents of nuclear SCF ubiquitin ligase complex (GO:0043224)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
nuclear SCF ubiquitin ligase complex [is_a relation] is_a  nuclear ubiquitin ligase complex (GO:0000152)
nuclear SCF ubiquitin ligase complex [is_a relation] is_a  SCF ubiquitin ligase complex (GO:0019005)
nuclear SCF ubiquitin ligase complex [BFO:0000050 relation] BFO:0000050  nucleus (GO:0005634)

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None.