Tim22 complex, mitochondrial inner membrane protein insertion complex, mitochondrial protein translocase complex
Alternate IDs
None
Definition
A multi-subunit complex embedded in the mitochondrial inner membrane that mediates the inner membrane insertion of multi-transmembrane spanning proteins that contain internal targeting elements. In yeast cells, TIM22 is a 300-kDa complex, consisting of four membrane integral subunits, Tim22, Tim54, Tim18 and Sdh3, and a peripheral chaperone complex consisting of the small TIM proteins, Tim9-Tim10-Tim12.
Source:PMID:12191765,
PMID:27554484