Planteome: Term Details for "aspartic endopeptidase activity, intramembrane cleaving" (GO:0042500)

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Term Information

Accession: GO:0042500
Name: aspartic endopeptidase activity, intramembrane cleaving
Ontology: molecular_function
Synonyms: None
Alternate IDs: None
Definition: Catalysis of the hydrolysis of nonterminal peptide bonds in a polypeptide chain, occurring within a membrane. Source: ISBN:0198506732, GOC:jl
Comment: Note that although GO generally avoids the use of localization information in terms, in this case an exception was made. This is because the fact that the cleavage occurs within the membrane is integral to its function, as it is the only thing that distinguishes this group from other aspartic endopeptidases.
History: See term history for GO:0042500 at QuickGO
Subset: None
Related: Link to all annotated objects annotated to aspartic endopeptidase activity, intramembrane cleaving.; Link to all direct and indirect annotations to aspartic endopeptidase activity, intramembrane cleaving.; Link to all direct and indirect annotations download (limited to first 10,000) for aspartic endopeptidase activity, intramembrane cleaving.
Feedback: Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

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BFO:0000001 entity
BFO:0000003 occurrent
BFO:0000015 process
GO:0003674 molecular_function
GO:0003824 catalytic activity
GO:0140096 catalytic activity, acting on a protein
GO:0016787 hydrolase activity
GO:0008233 peptidase activity
GO:0070001 aspartic-type peptidase activity
GO:0004175 endopeptidase activity
GO:0004190 aspartic-type endopeptidase activity
GO:0042500 aspartic endopeptidase activity, intramembrane cleaving

Parents of aspartic endopeptidase activity, intramembrane cleaving (GO:0042500)

subject	relation	object
aspartic endopeptidase activity, intramembrane cleaving	is_a	aspartic-type endopeptidase activity (GO:0004190)

This term has no children.

EC: 3.4.23.-
Reactome: R-HSA-9708457; R-HSA-8863101