Term Information

Accession
GO:0042500
Name
aspartic endopeptidase activity, intramembrane cleaving
Ontology
molecular_function
Synonyms
None
Alternate IDs
None
Definition
Catalysis of the hydrolysis of nonterminal peptide bonds in a polypeptide chain, occurring within a membrane. Source: ISBN:0198506732, GOC:jl
Comment
Note that although GO generally avoids the use of localization information in terms, in this case an exception was made. This is because the fact that the cleavage occurs within the membrane is integral to its function, as it is the only thing that distinguishes this group from other aspartic endopeptidases.
History
See term history for GO:0042500 at QuickGO
Subset
None
Feedback
Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

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Parents of aspartic endopeptidase activity, intramembrane cleaving (GO:0042500)
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aspartic endopeptidase activity, intramembrane cleaving [is_a relation] is_a  aspartic-type endopeptidase activity (GO:0004190)

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