Planteome: Term Details for "aspartic-type endopeptidase activity" (GO:0004190)

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Term Information

Accession: GO:0004190
Name: aspartic-type endopeptidase activity
Ontology: molecular_function
Synonyms: aspartic endopeptidase activity, aspartate protease activity, aspartic protease activity, aspartyl protease activity, carboxyl protease activity
Alternate IDs: None
Definition: Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which a water molecule bound by the side chains of aspartic residues at the active center acts as a nucleophile. Source: ISBN:0198506732
Comment: None
History: See term history for GO:0004190 at QuickGO
Subset: None
Related: Link to all annotated objects annotated to aspartic-type endopeptidase activity.; Link to all direct and indirect annotations to aspartic-type endopeptidase activity.; Link to all direct and indirect annotations download (limited to first 10,000) for aspartic-type endopeptidase activity.
Feedback: Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

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BFO:0000001 entity
BFO:0000003 occurrent
BFO:0000015 process
GO:0003674 molecular_function
GO:0003824 catalytic activity
GO:0140096 catalytic activity, acting on a protein
GO:0016787 hydrolase activity
GO:0008233 peptidase activity
GO:0070001 aspartic-type peptidase activity
GO:0004175 endopeptidase activity
GO:0004190 aspartic-type endopeptidase activity
GO:0042500 aspartic endopeptidase activity, intramembrane cleaving
GO:1902944 aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process

Parents of aspartic-type endopeptidase activity (GO:0004190)

subject	relation	object
aspartic-type endopeptidase activity	is_a	aspartic-type peptidase activity (GO:0070001)
aspartic-type endopeptidase activity	is_a	endopeptidase activity (GO:0004175)

Children of aspartic-type endopeptidase activity (GO:0004190)

subject	relation	object
aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process (GO:1902944)	is_a	aspartic-type endopeptidase activity
aspartic endopeptidase activity, intramembrane cleaving (GO:0042500)	is_a	aspartic-type endopeptidase activity

EC: 3.4.23.-
Reactome: R-HSA-9017817; R-HSA-373705; R-HSA-9013361; R-HSA-2022412; R-HSA-157640; R-HSA-157353; R-HSA-2022403; R-HSA-2065357; R-HSA-2220988; R-HSA-9604294