Planteome: Term Details for "MKS complex" (GO:0036038)

Accession: GO:0036038
Name: MKS complex
Ontology: cellular_component
Synonyms: MKS module, B9 complex, tectonic complex, tectonic-like complex, TCTN-B9D complex
Alternate IDs: None
Definition: A protein complex that is located at the ciliary transition zone and consists of several proteins some of which are membrane bound. Acts as an organiser of transition zone inner structure, specifically the Y-shaped links, in conjunction with the NPHP complex. The MKS complex also acts as part of the selective barrier that prevents diffusion of proteins between the ciliary cytoplasm and cellular cytoplasm as well as between the ciliary membrane and plasma membrane. Source: GOC:sp, PMID:21422230, GOC:cilia, PMID:21725307, PMID:26595381, PMID:21565611, PMID:22179047, PMID:26982032, PMID:25869670
Comment: Although there is some evidence, it is still unclear if the MKS and NPHP complexes are constituents parts of the Y-shaped links or are simply responsible for aligning and attaching the Y-shaped links to the membrane and axoneme.
History: See term history for GO:0036038 at QuickGO
Subset: None
Related: Link to all annotated objects annotated to MKS complex.; Link to all direct and indirect annotations to MKS complex.; Link to all direct and indirect annotations download (limited to first 10,000) for MKS complex.
Feedback: Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

subject	relation	object
MKS complex	is_a	protein-containing complex (GO:0032991)
MKS complex	BFO:0000050	ciliary transition zone (GO:0035869)

MKS complex