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ciliary transition zone

Term Information

Accession
GO:0035869
Name
ciliary transition zone
Ontology
cellular_component
Synonyms
cilial transition zone, cilium transition zone, connecting cilium
Alternate IDs
None
Definition
A region of the cilium between the basal body and proximal segment that is characterized by Y-shaped assemblages that connect axonemal microtubules to the ciliary membrane. The ciliary transition zone appears to function as a gate that controls ciliary membrane composition and separates the cytosol from the ciliary plasm. Source: PMID:21422230, GOC:cilia, GOC:kmv
Comment
Depending on the species, this region may have a distinct geometrically shaped electron-dense structure within the axonemal lumen visible in electron microscopy images; most animals don't display this inner structure. The axoneme extends through the ciliary transition zone, but only consists of the outer doublets. The central pair, axonemal spokes, and dynein complexes are not found in this part of the ciliary shaft. Note that the connecting cilium of the photoreceptor cells is thought to be equivalent to the transition zone.
History
See term history for GO:0035869 at QuickGO
Subset
None
Feedback
Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

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Parents of ciliary transition zone (GO:0035869)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
ciliary transition zone [is_a relation] is_a  cellular anatomical entity (GO:0110165)
ciliary transition zone [BFO:0000050 relation] BFO:0000050  cilium (GO:0005929)
Children of ciliary transition zone (GO:0035869)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
ciliary base (GO:0097546) [BFO:0000051 relation] BFO:0000051  ciliary transition zone
central cylinder (GO:1990805) [BFO:0000050 relation] BFO:0000050  ciliary transition zone
ciliary necklace (GO:0097538) [BFO:0000050 relation] BFO:0000050  ciliary transition zone
Y-shaped link (GO:0097537) [BFO:0000050 relation] BFO:0000050  ciliary transition zone
photoreceptor connecting cilium (GO:0032391) [is_a relation] is_a  ciliary transition zone
NPHP complex (GO:1990957) [BFO:0000050 relation] BFO:0000050  ciliary transition zone
MKS complex (GO:0036038) [BFO:0000050 relation] BFO:0000050  ciliary transition zone
None.