Planteome: Term Details for "activation of cysteine-type endopeptidase activity involved in apoptotic process" (GO:0006919)

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Term Information

Accession: GO:0006919
Name: activation of cysteine-type endopeptidase activity involved in apoptotic process
Ontology: biological_process
Synonyms: caspase activation, activation of caspase activity, activation of metacaspase activity
Alternate IDs: None
Definition: Any process that initiates the activity of the inactive enzyme cysteine-type endopeptidase in the context of an apoptotic process. Source: GOC:al, GOC:dph, GOC:tb, PMID:18328827, GOC:jl, PMID:14744432, Wikipedia:Caspase, GOC:mtg_apoptosis
Comment: This term should be used when the annotation refers to a process that occurs in a context of apoptotic cell death. To annotate gene products involved in activation of cysteine-type endopeptidases in other cellular process (e.g., cell cycle arrest) that do not necessarily develop into an apoptotic process, please use the more general parent term GO:0097202. Examples of 'activation of cysteine-type endopeptidase activity involved in apoptotic process' are cytochrome c and Apaf1. When cytochrome c is released from mitochondria and forms a complex with Apaf1, they form a scaffolding platform in which the pro-caspase 9 is bound (the 'apoptosome'). The caspase is then cleaved and activated. Cytochrome c and Apaf1 are therefore involved in the conversion of the zymogen procaspase 9 to the active form of the caspase.
History: See term history for GO:0006919 at QuickGO
Subset: gocheck_do_not_annotate
Related: Link to all annotated objects annotated to activation of cysteine-type endopeptidase activity involved in apoptotic process.; Link to all direct and indirect annotations to activation of cysteine-type endopeptidase activity involved in apoptotic process.; Link to all direct and indirect annotations download (limited to first 10,000) for activation of cysteine-type endopeptidase activity involved in apoptotic process.
Feedback: Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

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GO:0065007 biological regulation
GO:0008150 biological_process
BFO:0000001 entity
GO:0008152 metabolic process
BFO:0000003 occurrent
GO:0050789 regulation of biological process
GO:0043170 macromolecule metabolic process
GO:0003674 molecular_function
GO:0006807 nitrogen compound metabolic process
GO:0071704 organic substance metabolic process
GO:0048518 positive regulation of biological process
GO:0044238 primary metabolic process
BFO:0000015 process
GO:0019222 regulation of metabolic process
GO:0003824 catalytic activity
GO:1901564 organonitrogen compound metabolic process
GO:0009893 positive regulation of metabolic process
GO:0019538 protein metabolic process
GO:0060255 regulation of macromolecule metabolic process
GO:0065009 regulation of molecular function
GO:0051171 regulation of nitrogen compound metabolic process
GO:0080090 regulation of primary metabolic process
GO:0016787 hydrolase activity
GO:0010604 positive regulation of macromolecule metabolic process
GO:0044093 positive regulation of molecular function
GO:0051173 positive regulation of nitrogen compound metabolic process
GO:0006508 proteolysis
GO:0050790 regulation of catalytic activity
GO:0051246 regulation of protein metabolic process
GO:0140096 catalytic activity, acting on a protein
GO:0009987 cellular process
GO:0008233 peptidase activity
GO:0043085 positive regulation of catalytic activity
GO:0051247 positive regulation of protein metabolic process
GO:0051336 regulation of hydrolase activity
GO:0030162 regulation of proteolysis
GO:0008219 cell death
GO:0004175 endopeptidase activity
GO:0051345 positive regulation of hydrolase activity
GO:0045862 positive regulation of proteolysis
GO:0052547 regulation of peptidase activity
GO:0004197 cysteine-type endopeptidase activity
GO:0008234 cysteine-type peptidase activity
GO:0010952 positive regulation of peptidase activity
GO:0012501 programmed cell death
GO:0052548 regulation of endopeptidase activity
GO:0006915 apoptotic process
GO:0097153 cysteine-type endopeptidase activity involved in apoptotic process
GO:0010950 positive regulation of endopeptidase activity
GO:2000116 regulation of cysteine-type endopeptidase activity
GO:2001056 positive regulation of cysteine-type endopeptidase activity
GO:0043281 regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c

Parents of activation of cysteine-type endopeptidase activity involved in apoptotic process (GO:0006919)

subject	relation	object
activation of cysteine-type endopeptidase activity involved in apoptotic process	is_a	positive regulation of cysteine-type endopeptidase activity involved in apoptotic process (GO:0043280)

Children of activation of cysteine-type endopeptidase activity involved in apoptotic process (GO:0006919)

subject	relation	object
activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c (GO:0008635)	is_a	activation of cysteine-type endopeptidase activity involved in apoptotic process

activation of cysteine-type endopeptidase activity involved in apoptotic process

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Parents of activation of cysteine-type endopeptidase activity involved in apoptotic process (GO:0006919)

Children of activation of cysteine-type endopeptidase activity involved in apoptotic process (GO:0006919)

None.