Term Information

Accession
GO:0005757
Name
mitochondrial permeability transition pore complex
Ontology
cellular_component
Synonyms
MPTP complex, mitochondrial PT pore complex, PTPC
Alternate IDs
None
Definition
A protein complex that connects the inner and outer membranes of animal mitochondria and acts as a pore that can open transiently to allow free diffusion of solutes between the mitochondrial matrix and the cytosol. The pore complex is formed of the voltage-dependent anion channel (VDAC), the adenine nucleotide translocase (ANT) and cyclophilin-D (CyP-D). Source: PMID:10393078
Comment
None
History
See term history for GO:0005757 at QuickGO
Subset
None
Feedback
Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

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Parents of mitochondrial permeability transition pore complex (GO:0005757)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
mitochondrial permeability transition pore complex [is_a relation] is_a  pore complex (GO:0046930)
mitochondrial permeability transition pore complex [is_a relation] is_a  mitochondrial protein-containing complex (GO:0098798)
mitochondrial permeability transition pore complex [BFO:0000050 relation] BFO:0000050  mitochondrial envelope (GO:0005740)

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None.