Term Information

Accession
GO:0005744
Name
TIM23 mitochondrial import inner membrane translocase complex
Ontology
cellular_component
Synonyms
Tim23 complex, mitochondrial inner membrane pre-sequence translocase complex, mitochondrial inner membrane presequence translocase complex, mitochondrial inner membrane translocase complex
Alternate IDs
None
Definition
The protein transport machinery of the mitochondrial inner membrane that typically transports proteins that possess a matrix-targeting N-terminal presequence. The TIM23 complex contains three essential Tim proteins: Tim17 and Tim23 are thought to build a preprotein translocation channel while Tim44 interacts transiently with the matrix heat-shock protein Hsp70 to form an ATP-driven import motor. Source: PMID:8851659, PMID:27554484
Comment
See also the cellular component term 'mitochondrial inner membrane ; GO:0005743'.
History
See term history for GO:0005744 at QuickGO
Subset
goslim_pir
Feedback
Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

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Parents of TIM23 mitochondrial import inner membrane translocase complex (GO:0005744)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
TIM23 mitochondrial import inner membrane translocase complex [is_a relation] is_a  inner mitochondrial membrane protein complex (GO:0098800)
Children of TIM23 mitochondrial import inner membrane translocase complex (GO:0005744)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
PAM complex, Tim23 associated import motor (GO:0001405) [BFO:0000050 relation] BFO:0000050  TIM23 mitochondrial import inner membrane translocase complex
None.