Term Information

Accession
GO:0004823
Name
leucine-tRNA ligase activity
Ontology
molecular_function
Synonyms
leucyl-tRNA synthetase activity, L-leucine:tRNALeu ligase (AMP-forming), leucine translase activity, leucine-tRNA synthetase activity, leucyl-transfer RNA synthetase activity, leucyl-transfer ribonucleate synthetase activity, leucyl-transfer ribonucleic acid synthetase activity
Alternate IDs
None
Definition
Catalysis of the reaction: L-leucine + ATP + tRNA(Leu) = AMP + diphosphate + 2 H+ + Leu-tRNA(Leu). Source: RHEA:11688, EC:6.1.1.4
Comment
None
History
See term history for GO:0004823 at QuickGO
Subset
None
Feedback
Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

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Parents of leucine-tRNA ligase activity (GO:0004823)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
leucine-tRNA ligase activity [is_a relation] is_a  aminoacyl-tRNA ligase activity (GO:0004812)
Children of leucine-tRNA ligase activity (GO:0004823)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
negative regulation of leucine-tRNA ligase activity (GO:1903634) [RO:0002212 relation] RO:0002212  leucine-tRNA ligase activity
EC
6.1.1.4
KEGG_REACTION
R03657
MetaCyc
LEUCINE--TRNA-LIGASE-RXN
Reactome
R-HSA-380200
R-HSA-379974
RHEA
11688