Term Information

Accession
GO:1990788
Name
GLI-SUFU complex
Ontology
cellular_component
Synonyms
None
Alternate IDs
None
Definition
A protein repressing GLI's transcription factor activity when SMO signalling is inactive. Upon ligand binding to the upstream receptor PTC (Patched) GLI dissociates from SUFU and activates transcription of hedgehog-target genes. In mammals it consists of SUFU and one of the GLI family proteins. Source: PMID:24311597, GOC:bhm
Comment
An example of this is SUFU in human (Q9UMX1) in PMID:24311597 (inferred from direct assay).
History
See term history for GO:1990788 at QuickGO
Subset
None
Feedback
Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

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Parents of GLI-SUFU complex (GO:1990788)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
GLI-SUFU complex [is_a relation] is_a  protein-containing complex (GO:0032991)
GLI-SUFU complex [BFO:0000050 relation] BFO:0000050  cytosol (GO:0005829)

This term has no children.

None.