Planteome: Term Details for "PCSK9-LDLR complex" (GO:1990666)

Accession: GO:1990666
Name: PCSK9-LDLR complex
Ontology: cellular_component
Synonyms: PCSK9.LDLR complex, PCSK9/LDL-R complex, PCSK9:low-density lipoprotein receptor complex, PCSK9:EGF-A complex
Alternate IDs: None
Definition: A protein complex consisting of the serine protease PCSK9 (proprotein convertase subtilisin/kexin-9) and a low-density lipoprotein receptor (LDLR). Interaction typically occurs through the epidermal growth factor-like repeat A (EGF-A) domain of the LDLR, and complex formation promotes degradation of the LDLR through the endosome/lysosome pathway. Source: PMID:18250299, GOC:BHF, GOC:nc, PMID:24440079
Comment: None
History: See term history for GO:1990666 at QuickGO
Subset: None
Related: Link to all annotated objects annotated to PCSK9-LDLR complex.; Link to all direct and indirect annotations to PCSK9-LDLR complex.; Link to all direct and indirect annotations download (limited to first 10,000) for PCSK9-LDLR complex.
Feedback: Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

subject	relation	object
PCSK9-LDLR complex	is_a	protein-containing complex (GO:0032991)

This term has no children.

PCSK9-LDLR complex