Term Information

Accession
GO:1990664
Name
Nkx-2.5 complex
Ontology
cellular_component
Synonyms
NKX.2-5 homodimer complex, NKX2.5 complex, NKX2E homodimer complex, Nkx-2.5 homodimer complex
Alternate IDs
None
Definition
A transcription factor complex formed by two or more subunits of Nkx-2.5. Nkx-2.5 is an evolutionary conserved transcription factor important for the specification and differentiation of cardiomyocytes during heart development. It is also required for spleen development. It binds DNA either as a monomer, or a homodimer, or a heterodimer complex to activate or inhibit expression of genes. Source: PMID:22849347, GOC:ame
Comment
An example of this is Nkx-2.5 in human (UniProt symbol P52952) in PMID:22849347 (inferred from direct assay).
History
See term history for GO:1990664 at QuickGO
Subset
None
Feedback
Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

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Parents of Nkx-2.5 complex (GO:1990664)
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Nkx-2.5 complex [is_a relation] is_a  RNA polymerase II transcription regulator complex (GO:0090575)

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None.