Term Information

Accession
GO:1990513
Name
CLOCK-BMAL transcription complex
Ontology
cellular_component
Synonyms
CLOCK/BMAL complex
Alternate IDs
None
Definition
Transcription factor complex which interacts with E-box regulatory elements in target genes, including Period (Per1, Per2, Per3) and Cryptochrome (Cry1, Cry2), to activate their transcription during the daytime. The CRY-PER complexes inhibit CLOCK-BMAL1-driven transcription in a negative feedback loop to generate circadian rhythms. Source: PMID:23229515, GOC:bhm
Comment
An example of this is CLOCK in human (O15516) in PMID:23229515 (inferred from physical interaction).
History
See term history for GO:1990513 at QuickGO
Subset
None
Feedback
Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

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Parents of CLOCK-BMAL transcription complex (GO:1990513)
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CLOCK-BMAL transcription complex [is_a relation] is_a  RNA polymerase II transcription regulator complex (GO:0090575)

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None.