Component of the core exon-exon-junction complex (EJC). Fairly conserved in eukaryotes; in Drosophila, consists of the Mago and Y14 (tsunagi) gene products. Important for coupling nuclear and cytoplasmic events in gene expression. Inhibits the ATPase activity of eIF4AIII (Q9VHS8) to ensure a stable association of the EJC core with the mRNA.
Source:PMID:12730685,
GOC:bhm
Comment
An example of this is Mago in drome (P49028) in PMID:12730685 (inferred from direct assay).