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MTREC complex

Term Information

Accession
GO:1990477
Name
MTREC complex
Ontology
cellular_component
Synonyms
Mtl1-Red1 core complex, NURS complex, PAXT complex
Alternate IDs
GO:1990345
Definition
Protein complex formed by an RNA binding protein Red1, an RNA helicase Mtl1, Red5, Rmn1, Iss10/Pir1, and Ars2/Pir2. This complex is required for the recruitment of the nuclear exosome to Mmi1 nuclear focus. It is likely related to the human CBCN complex. This complex is also known as RNA silencing (NURS) complex. Source: PMID:24210919, PMID:32012158, PMID:24713849
Comment
An example of this is the complex formed by Red1 and Mtl1 in S. pombe (UniProt symbols Q9UTR8 and O13799 respectively) in PMID:24210919 (inferred from direct assay).
History
See term history for GO:1990477 at QuickGO
Subset
None
Feedback
Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

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Parents of MTREC complex (GO:1990477)
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MTREC complex [is_a relation] is_a  nuclear protein-containing complex (GO:0140513)

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None.