Term Information

Accession
GO:1990455
Name
PTEN phosphatase complex
Ontology
cellular_component
Synonyms
phosphatase and tensin homolog, phosphatase and tensin homolog deleted on chromosome ten homodimer, phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN homodimer
Alternate IDs
None
Definition
A phospholipid phosphatase complex that catalyses the hydrolysis of the second messenger PtdIns (3,4,5)P3. Will also dephosphorylate PtdIns(3,4)P2, PtdIns3P, and Ins(1,3,4,5)P4. Dimerization is critical for its lipid phosphatase function. Source: PMID:24766807, GOC:bhm
Comment
An example of this is PTEN in human (P60484) in PMID:24766807 (inferred from direct assay).
History
See term history for GO:1990455 at QuickGO
Subset
None
Feedback
Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

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Parents of PTEN phosphatase complex (GO:1990455)
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PTEN phosphatase complex [is_a relation] is_a  phosphatidylinositol phosphate phosphatase complex (GO:1904144)

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None.