A protein complex capable of sequence-specific DNA binding RNA polymerase II transcription factor activity through binding to a symmetrical DNA sequence (E-boxes) (5'-CACGTG-3'). Found in a variety of viral and cellular promoters.
Source:PMID:8576131,
GOC:bhm
Comment
An example of this is USF1 in human (UniProt symbol P22415) in PMID:8576131 (inferred from direct assay).