Planteome: Term Details for "UBR1-RAD6 ubiquitin ligase complex" (GO:1990303)

Accession: GO:1990303
Name: UBR1-RAD6 ubiquitin ligase complex
Ontology: cellular_component
Synonyms: UBR1-RAD6 complex
Alternate IDs: None
Definition: A ubiquitin ligase complex consisting of UBR1 and RAD6 components. It polyubiquitinates proteins containing non-acetylated N-terminal residues causing their subsequent degradation by the proteasome as part of the Ac/N-End Rule pathway. It recognizes non-acetylated N-terminal methionine if it is followed by a hydrophobic residue. Additionally, it acts in an N-end rule independent manner as a component of a novel quality control pathway for proteins synthesized on cytosolic ribosomes. Source: PMID:19531475, GOC:bhm
Comment: This complex has been identified in Saccharomyces cerevisiae (P19812) - see PMID:19531475 (inferred from direct assay).
History: See term history for GO:1990303 at QuickGO
Subset: None
Related: Link to all annotated objects annotated to UBR1-RAD6 ubiquitin ligase complex.; Link to all direct and indirect annotations to UBR1-RAD6 ubiquitin ligase complex.; Link to all direct and indirect annotations download (limited to first 10,000) for UBR1-RAD6 ubiquitin ligase complex.
Feedback: Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

subject	relation	object
UBR1-RAD6 ubiquitin ligase complex	is_a	intracellular protein-containing complex (GO:0140535)
UBR1-RAD6 ubiquitin ligase complex	is_a	transferase complex (GO:1990234)

This term has no children.

UBR1-RAD6 ubiquitin ligase complex