Planteome: Term Details for "platelet-derived growth factor receptor-ligand complex" (GO:1990270)

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Term Information

Accession: GO:1990270
Name: platelet-derived growth factor receptor-ligand complex
Ontology: cellular_component
Synonyms: PDGF receptor-ligand complex, PDGF-AA-receptor alpha complex, PDGF-AB-receptor alpha complex, PDGF-AB-receptor beta complex, PDGF-BB-receptor alpha complex, PDGF-BB-receptor alpha-beta complex, PDGF-BB-receptor beta complex, PDGF-CC-receptor alpha complex, PDGF-CC-receptor alpha-beta complex, PDGF-CC-receptor beta complex, PDGF-DD-receptor alpha-beta complex, PDGF-DD-receptor beta complex, PDGF complex, receptor-ligand complex
Alternate IDs: None
Definition: A tetrameric protein complex consisting of two platelet-derived growth factor (PDGF) receptor subunits and two PDGF ligand subunits. Binding of the PDGF ligand dimer to the PDGF receptor in the plasma membrane induces receptor dimerisation and activation. PDGFs are involved in a wide variety of signalling processes and are found in all vertebrates. At least two different receptor chains (A and B) and four types of ligand chains (A, B, C, and D) are known forming a wide variety of combinations of receptor-ligand complexes. Source: PMID:11331882, GOC:bhm
Comment: An example of this is PDGFA-PGFRA in human (UniProt symbols P04085, P16234) in PMID:7679113 (inferred from direct assay).
History: See term history for GO:1990270 at QuickGO
Subset: None
Related: Link to all annotated objects annotated to platelet-derived growth factor receptor-ligand complex.; Link to all direct and indirect annotations to platelet-derived growth factor receptor-ligand complex.; Link to all direct and indirect annotations download (limited to first 10,000) for platelet-derived growth factor receptor-ligand complex.
Feedback: Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

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GO:0005575 cellular_component
GO:0110165 cellular anatomical entity
GO:0071944 cell periphery
GO:0016020 membrane
GO:0032991 protein-containing complex
GO:0098796 membrane protein complex
GO:0005886 plasma membrane
GO:0098797 plasma membrane protein complex
GO:1990270 platelet-derived growth factor receptor-ligand complex

Parents of platelet-derived growth factor receptor-ligand complex (GO:1990270)

subject	relation	object
platelet-derived growth factor receptor-ligand complex	BFO:0000051	receptor complex (GO:0043235)
platelet-derived growth factor receptor-ligand complex	BFO:0000051	platelet-derived growth factor complex (GO:1990265)
platelet-derived growth factor receptor-ligand complex	is_a	plasma membrane protein complex (GO:0098797)

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platelet-derived growth factor receptor-ligand complex

Term Information

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Parents of platelet-derived growth factor receptor-ligand complex (GO:1990270)

None.