Planteome: Term Details for "macrolide transmembrane transporter complex" (GO:1990195)

Notice

Some functionality on this page depends on JavaScript. To fully use the features of AmiGO 2, enable JavaScript in your browser and reload from the landing page.

Term Information

Accession: GO:1990195
Name: macrolide transmembrane transporter complex
Ontology: cellular_component
Synonyms: macrolide transporter, AcrAB-TolC complex, MacAB-TolC complex, macrolide transporter complex
Alternate IDs: None
Definition: A bacterial transmembrane transporter complex that spans the entire cell membrane system and possesses ATP-dependent xenobiotic transport activity pumping drugs (typically antibiotics) and other toxins directly from the cytosol out of the bacterial cell. Typically, it is trimeric consisting of a inner membrane ATPase (IMP), a periplasmic membrane fusion protein (MFP) and an outer membrane factor (OMF). In E. coli, macrolide transporter complexes may consists of MacB (IMP), MacA (MFP) and TolC (OMF) or AcrB (IMP), AcrA (MFP) and TolC (OMF). Trimeric TolC is a common OMF found in many macrolide transporter complexes. Source: PMID:10879525, PMID:18955484, PMID:19254725, GOC:bhm
Comment: None
History: See term history for GO:1990195 at QuickGO
Subset: None
Related: Link to all annotated objects annotated to macrolide transmembrane transporter complex.; Link to all direct and indirect annotations to macrolide transmembrane transporter complex.; Link to all direct and indirect annotations download (limited to first 10,000) for macrolide transmembrane transporter complex.
Feedback: Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.