Term Information

Accession
GO:1990144
Name
intrinsic apoptotic signaling pathway in response to hypoxia
Ontology
biological_process
Synonyms
None
Alternate IDs
None
Definition
The series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced in response to hypoxia (lowered oxygen tension). Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level. The pathway ends when the execution phase of apoptosis is triggered. Source: PMID:20436456, GOC:BHF, GOC:mtg_apoptosis, GOC:rl
Comment
None
History
See term history for GO:1990144 at QuickGO
Subset
None
Feedback
Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

Filter results

Loading...
pending...
Parents of intrinsic apoptotic signaling pathway in response to hypoxia (GO:1990144)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
intrinsic apoptotic signaling pathway in response to hypoxia [BFO:0000050 relation] BFO:0000050  cellular response to hypoxia (GO:0071456)
intrinsic apoptotic signaling pathway in response to hypoxia [is_a relation] is_a  intrinsic apoptotic signaling pathway (GO:0097193)
Children of intrinsic apoptotic signaling pathway in response to hypoxia (GO:1990144)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway (GO:1903298) [RO:0002212 relation] RO:0002212  intrinsic apoptotic signaling pathway in response to hypoxia
regulation of hypoxia-induced intrinsic apoptotic signaling pathway (GO:1903297) [RO:0002211 relation] RO:0002211  intrinsic apoptotic signaling pathway in response to hypoxia
None.