Term Information

Accession
GO:1990144
Name
intrinsic apoptotic signaling pathway in response to hypoxia
Ontology
biological_process
Synonyms
None
Alternate IDs
None
Definition
The series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced in response to hypoxia (lowered oxygen tension). Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level. The pathway ends when the execution phase of apoptosis is triggered. Source: PMID:20436456, GOC:BHF, GOC:mtg_apoptosis, GOC:rl
Comment
None
History
See term history for GO:1990144 at QuickGO
Subset
None
Feedback
Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

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Parents of intrinsic apoptotic signaling pathway in response to hypoxia (GO:1990144)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
intrinsic apoptotic signaling pathway in response to hypoxia [is_a relation] is_a  intrinsic apoptotic signaling pathway (GO:0097193)
intrinsic apoptotic signaling pathway in response to hypoxia [BFO:0000050 relation] BFO:0000050  cellular response to hypoxia (GO:0071456)
Children of intrinsic apoptotic signaling pathway in response to hypoxia (GO:1990144)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway (GO:1903298) [RO:0002212 relation] RO:0002212  intrinsic apoptotic signaling pathway in response to hypoxia
regulation of hypoxia-induced intrinsic apoptotic signaling pathway (GO:1903297) [RO:0002211 relation] RO:0002211  intrinsic apoptotic signaling pathway in response to hypoxia
None.