Term Information

Accession
GO:1990077
Name
primosome complex
Ontology
cellular_component
Synonyms
primosome
Alternate IDs
None
Definition
Any of a family of protein complexes that form at the origin of replication or stalled replication forks and function in replication primer synthesis in all organisms. Early complexes initiate double-stranded DNA unwinding. The core unit consists of a replicative helicase and a primase. The helicase further unwinds the DNA and recruits the polymerase machinery. The primase synthesizes RNA primers that act as templates for complementary stand replication by the polymerase machinery. The primosome contains a number of associated proteins and protein complexes and contributes to the processes of replication initiation, lagging strand elongation, and replication restart. Source: PMID:21856207, GOC:mah, GOC:bhm
Comment
None
History
See term history for GO:1990077 at QuickGO
Subset
None
Feedback
Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

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Parents of primosome complex (GO:1990077)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
primosome complex [BFO:0000050 relation] BFO:0000050  replisome (GO:0030894)
primosome complex [is_a relation] is_a  protein-DNA complex (GO:0032993)
Children of primosome complex (GO:1990077)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
core primosome complex (GO:1990098) [is_a relation] is_a  primosome complex
pre-primosome complex (GO:1990099) [is_a relation] is_a  primosome complex
DnaB-DnaC complex (GO:1990100) [BFO:0000050 relation] BFO:0000050  primosome complex
DnaA-DiaA complex (GO:1990102) [is_a relation] is_a  primosome complex
DnaA-HU complex (GO:1990103) [is_a relation] is_a  primosome complex
DnaA-oriC complex (GO:1990101) [is_a relation] is_a  primosome complex
None.