Planteome: Term Details for "amyloid fibril formation" (GO:1990000)

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Term Information

Accession: GO:1990000
Name: amyloid fibril formation
Ontology: biological_process
Synonyms: amyloid fibril assembly, amyloid structure assembly, amyloid structure formation
Alternate IDs: None
Definition: The generation of amyloid fibrils, insoluble fibrous protein aggregates exhibiting beta sheet structure, from proteins. Source: GOC:jj, GOC:ppm, GOC:cvs, PMID:28937655, PMID:21148556, GOC:sj, PMID:22817896, PMID:29654159
Comment: Although deposition of amyloid fibrils is associated with diseases, e.g. Alzheimer's disease, amyloid formation is a normal process. Disease occurs when the balance between amyloid formation and clearance is disrupted (reviewed e.g. in PMID:29654159 and PMID:28937655). An example of a normal amyloid complex is composed of human RIP1 and RIP3 kinases (PMID:22817896).
History: See term history for GO:1990000 at QuickGO
Subset: None
Related: Link to all annotated objects annotated to amyloid fibril formation.; Link to all direct and indirect annotations to amyloid fibril formation.; Link to all direct and indirect annotations download (limited to first 10,000) for amyloid fibril formation.
Feedback: Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

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BFO:0000001 entity
BFO:0000003 occurrent
GO:0008150 biological_process
BFO:0000015 process
GO:0009987 cellular process
GO:0008152 metabolic process
GO:0071840 cellular component organization or biogenesis
GO:0006807 nitrogen compound metabolic process
GO:0071704 organic substance metabolic process
GO:0016043 cellular component organization
GO:0043170 macromolecule metabolic process
GO:1901564 organonitrogen compound metabolic process
GO:0044238 primary metabolic process
GO:0019538 protein metabolic process
GO:0097435 supramolecular fiber organization
GO:1990000 amyloid fibril formation
GO:1905907 negative regulation of amyloid fibril formation
GO:1905908 positive regulation of amyloid fibril formation
GO:1905906 regulation of amyloid fibril formation

Parents of amyloid fibril formation (GO:1990000)

subject	relation	object
amyloid fibril formation	is_a	protein metabolic process (GO:0019538)
amyloid fibril formation	is_a	supramolecular fiber organization (GO:0097435)

Children of amyloid fibril formation (GO:1990000)

subject	relation	object
regulation of amyloid fibril formation (GO:1905906)	RO:0002211	amyloid fibril formation
positive regulation of amyloid fibril formation (GO:1905908)	RO:0002213	amyloid fibril formation
negative regulation of amyloid fibril formation (GO:1905907)	RO:0002212	amyloid fibril formation

amyloid fibril formation

Term Information

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Parents of amyloid fibril formation (GO:1990000)

Children of amyloid fibril formation (GO:1990000)

None.