Term Information

Accession
GO:1904602
Name
serotonin-activated cation-selective channel complex
Ontology
cellular_component
Synonyms
5-HT-3 receptor complex, 5-HT3 receptor complex, 5-hydroxytryptamine receptor 3 complex, 5HT3 receptor complex, serotonin receptor complex
Alternate IDs
None
Definition
A protein complex which is capable of serotonin-activated cation-selective channel activity. Mainly found in pre- and postsynaptic membranes of the brain and gastrointestinal tract. Depending on its location it transports Ca2+, Mg2+, Na+ or K+. It is always a pentamer, containing at least the 5HT3A subunit forming 5HT3A homopentamers or 5HT3A/B heteropentamers. In human, 5HT3A/C, A/D and A/E heteropentamers also exist. Source: PMID:16116092, GOC:TermGenie, GO_REF:0000088, GOC:bhm
Comment
An example of this is HTR3A in human (P46098) in PMID:16116092 (inferred from direct assay).
History
See term history for GO:1904602 at QuickGO
Subset
None
Feedback
Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

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Parents of serotonin-activated cation-selective channel complex (GO:1904602)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
serotonin-activated cation-selective channel complex [is_a relation] is_a  neurotransmitter receptor complex (GO:0098878)
serotonin-activated cation-selective channel complex [is_a relation] is_a  serotonin receptor complex (GO:0098665)
serotonin-activated cation-selective channel complex [is_a relation] is_a  cation channel complex (GO:0034703)

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None.