Term Information

Accession
GO:0170010
Name
nonsense-mediated decay complex
Ontology
cellular_component
Synonyms
Upf complex
Alternate IDs
None
Definition
A highly conserved protein complex that recognises and elicits the rapid degradation of mRNAs in which an amino-acid codon has changed to a nonsense codon; occurs when the 3' end is not protected by a 3'-poly(A) tail; degradation proceeds in the 3' to 5' direction. Source: GOC:lnp, PMID:29282598, PMID:1569946, PMID:9032286
Comment
None
History
See term history for GO:0170010 at QuickGO
Subset
None
Feedback
Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

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Parents of nonsense-mediated decay complex (GO:0170010)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
nonsense-mediated decay complex [is_a relation] is_a  catalytic complex (GO:1902494)

This term has no children.

IntAct
EBI-16420380