Term Information

Accession
GO:0160005
Name
PAT complex
Ontology
cellular_component
Synonyms
None
Alternate IDs
None
Definition
A transmembrane protein complex located in the endoplasmic reticulum (ER) involved in the correct folding of multipass membrane proteins in the ER membrane. In human, the substrate-binding Asterix (PAT10, WDR83OS) forms an obligate heterodimer with CCDC47. Source: PMID:33082068, PMID:32814900, PMID:33960686
Comment
PAT complex functions by shielding exposed hydrophilicity of transmembrane domains (TMDs) to prevent premature degradation and promote proper folding and bundling of TMDs.
History
See term history for GO:0160005 at QuickGO
Subset
None
Feedback
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Parents of PAT complex (GO:0160005)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
PAT complex [is_a relation] is_a  endoplasmic reticulum protein-containing complex (GO:0140534)
PAT complex [BFO:0000050 relation] BFO:0000050  endoplasmic reticulum membrane (GO:0005789)
PAT complex [is_a relation] is_a  membrane protein complex (GO:0098796)

This term has no children.

None.