Term Information

Accession
GO:0140672
Name
ATAC complex
Ontology
cellular_component
Synonyms
ADA2A-containing complex, Ada Two-A containing complex, Ada two A containing complex, Ada-Two-A-containing complex, G-ATAC complex, KAT2A-containing ATAC complex, KAT2B-containing ATAC complex
Alternate IDs
None
Definition
A chromatin remodeling complex that regulates transcription via acetylation primarily of nucleosomal histones H3 and possibly H4. Shares the histone acetylation (HAT) module of GCN5/PCAF-ADA2-ADA3-SGF29 (or orthologs) with the related SAGA complex (GO:0000124). Contains HAT subunits GCN5 or PCAF in a mutually exclusive manner. In addition to the HAT module contains DR1/NC2B, KAT14, MBIP, WDR5, YEATS2 and ZZZ3 or orthologs. Also regulates the activity of non-histone targets and orchestrates mitotic progression by regulating Cyclin A degradation through acetylation. Source: PMID:19936620, PMID:28966424, PMID:20562830, GOC:bhm
Comment
None
History
See term history for GO:0140672 at QuickGO
Subset
None
Feedback
Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

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Parents of ATAC complex (GO:0140672)
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ATAC complex [is_a relation] is_a  SAGA-type complex (GO:0070461)

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None.