Term Information

Accession
GO:0140416
Name
DNA-binding transcription factor inhibitor activity
Ontology
molecular_function
Synonyms
None
Alternate IDs
None
Definition
An activity that stops, prevents, or reduces the activity of a DNA binding transcription factor activity. Source: PMID:10652346
Comment
An example is TCF23 Q7RTU1 is an example of a protein that regulates transcription factors by heterodimerising or binding to DbTFs and prevent DNA binding and their specific genomic binding site where the dbTF would have activated or repressed transcription. Also an example is NFKBIA P25963 which has a different way of regulating transcription factor activity by sequestering the dbTF (complex) in the cytoplasm. Another example is the HSP90 and HSP23 proteins that sequester steroid receptors away from the DNA.
History
See term history for GO:0140416 at QuickGO
Subset
None
Feedback
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Parents of DNA-binding transcription factor inhibitor activity (GO:0140416)
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DNA-binding transcription factor inhibitor activity [is_a relation] is_a  molecular function regulator (GO:0098772)

This term has no children.

None.