Term Information

Accession
GO:0140080
Name
class III/IV DNA-(apurinic or apyrimidinic site) endonuclease activity
Ontology
molecular_function
Synonyms
endonuclease III, endonuclease IV
Alternate IDs
None
Definition
Catalysis of the cleavage of an AP site 3' and 5' of the baseless site, generating a 3'-phosphate and a 5'-OH. Source: PMID:2519777
Comment
Note that this term is does not have parentage in the 'nuclease activity' branch of the ontology because both GO and the Enzyme Commission define nuclease activity as a type of hydrolysis. Class II AP endonuclease is a nuclease, but not Class I, III and IV.
History
See term history for GO:0140080 at QuickGO
Subset
None
Feedback
Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

Filter results

Loading...
pending...
Parents of class III/IV DNA-(apurinic or apyrimidinic site) endonuclease activity (GO:0140080)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
class III/IV DNA-(apurinic or apyrimidinic site) endonuclease activity [is_a relation] is_a  DNA-(apurinic or apyrimidinic site) endonuclease activity (GO:0003906)

This term has no children.

Wikipedia
AP_endonuclease