Planteome logo

PAR polarity complex

Term Information

Accession
GO:0120157
Name
PAR polarity complex
Ontology
cellular_component
Synonyms
apical polarity complex, BEM1-CDC24-CLA4 complex, Cdc42p GEF-PAK complex, PAR3-PAR6-atypical PKC, PAR3/PAR6/aPKC, PAR6-PAR3-aPKC complex
Alternate IDs
None
Definition
A protein kinase complex that is required for the establishment of a cell polarity axis during the cell division cycle. Binds directly to activated CDC42 GTPase and is required for orchestrating a cellular gradient of CDC42. In S. cerevisiae components are: BEM1, CDC24 and CLA4; from worms to vertebrates it contains a PAR6 protein, PAR3 protein and an atypical PKC. Source: PMID:18005931, PMID:28682236, GOC:lnp, PMID:11113154, PMID:22500799
Comment
"This tripartite complex named PAR6/PAR3/aPKC is conserved from worms to vertebrates" (PMID:18005931). In yeast, the components are BEM1, CDC24, and CLA4.
History
See term history for GO:0120157 at QuickGO
Subset
None
Feedback
Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

Filter results

Loading...
pending...
Parents of PAR polarity complex (GO:0120157)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
PAR polarity complex [is_a relation] is_a  serine/threonine protein kinase complex (GO:1902554)

This term has no children.

None.