Term Information

Accession
GO:0099126
Name
transforming growth factor beta complex
Ontology
cellular_component
Synonyms
TGF-beta complex, TGF-beta dimer, TGFB complex, TGFB dimer, TGFbeta complex, TGFbeta dimer
Alternate IDs
None
Definition
A protein complex acting as ligand of the transforming growth factor beta receptor complex, typically a homodimer of any of the TFGbeta isoforms. The precursor of TGFbeta proteins is cleaved into mature TGFbeta and the latency-associated peptide (LAP), which remains non-covalently linked to mature TGFbeta rendering it inactive. TGFbeta is activated by dimerisation and dissociation of the LAP. Source: PMID:22943793, GOC:bhm
Comment
None
History
See term history for GO:0099126 at QuickGO
Subset
None
Feedback
Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

Filter results

Loading...
pending...
Parents of transforming growth factor beta complex (GO:0099126)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
transforming growth factor beta complex [is_a relation] is_a  protein-containing complex (GO:0032991)
transforming growth factor beta complex [BFO:0000050 relation] BFO:0000050  collagen-containing extracellular matrix (GO:0062023)

This term has no children.

None.