Term Information

Accession
GO:0098855
Name
HCN channel complex
Ontology
cellular_component
Synonyms
K/Na hyperpolarization-activated cyclic nucleotide-gated channel complex, potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel complex, potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 tetramer, potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 tetramer, HCN1 channel complex, HCN2 channel complex, HCN3 channel complex, HCN4 channel complex, K/Na hyperpolarization-activated channel 3 complex, K/Na hyperpolarization-activated cyclic nucleotide-gated channel 1 complex, K/Na hyperpolarization-activated cyclic nucleotide-gated channel 2 complex, K/Na hyperpolarization-activated cyclic nucleotide-gated channel 4 complex, potassium/sodium hyperpolarization-activated channel 3 complex, potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 complex, potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 complex, potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 complex
Alternate IDs
GO:1990746, GO:1990759
Definition
A cation ion channel with a preference for K+ over Na+ ions, which is activated by membrane hyperpolarization, and consists of a tetramer of HCN family members. Some members of this family (HCN1, HCN2 and HCN4) are also activated when cAMP binds to their cyclic nucleotide binding domain (CNBD). Channel complexes of this family play an important role in the control of pacemaker activity in the heart. Source: PMID:20829353
Comment
None
History
See term history for GO:0098855 at QuickGO
Subset
None
Feedback
Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

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Parents of HCN channel complex (GO:0098855)
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HCN channel complex [is_a relation] is_a  voltage-gated potassium channel complex (GO:0008076)

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